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Research Scientist I / II – High Throughput Chemistry

iambic-therapeuticsSan Diego HQScience
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Salary
$113K – $156K
Job type
Full-time
Experience
Mid
Posted
24 Sept 2026
Status
Open · checked 7d ago

About this role

Iambic Therapeutics is hiring a Research Scientist I / II in San Diego to drive high-throughput chemistry initiatives within the discovery team. This role suits professionals with a strong background in organic synthesis and automation who want to advance drug discovery pipelines.

Role Overview

Iambic Therapeutics seeks a Research Scientist I or II for the Discovery Chemistry team at the San Diego headquarters. The professional in this position utilizes expertise in catalysis, organic synthesis, and reaction development to run high-throughput experiments and manage compound library campaigns. The role involves cross-functional collaboration with biology, chemistry, AI/ML, software, and compound management groups to utilize the high-throughput experimentation platform.

Key Responsibilities

Create and run parallel synthetic procedures to produce large compound libraries.
Discover, build, and refine new synthetic techniques focused on automation compatibility and scalability.
Convert traditional bench-scale synthesis routes into automated, high-throughput processes.
Manage the upkeep, daily operation, and improvement of automated synthesis machinery and chemistry tools.
Review research findings and library data, sharing outcomes with interdisciplinary project teams.
Maintain safety guidelines and proper electronic laboratory notebook data recording habits.
Participate as a core member of an interdisciplinary team spanning software, chemistry, biology, and automation.
Resolve technical issues, find bottlenecks, and create solutions for automated workflows.

Requirements

Ph.D. in Organic Chemistry with zero to five years of industry experience, or an MS in Organic Chemistry with at least eight years of industry experience.
Proficiency in modern organic synthetic methods.
Practical, hands-on background in parallel synthesis and/or high-throughput chemistry.
Familiarity with liquid handling robotics, laboratory automation, and automated purification and analytical systems.
Capacity to adapt to a fast-moving, collaborative research setting.
Strong verbal and written communication abilities for explaining technical concepts.
Capability to handle shifting priorities and targets driven by biological data.

Nice to Have

Background in Direct-to-Biology drug discovery strategies.
Knowledge of medicinal chemistry principles.
Experience guiding junior colleagues or interns.

Skills and Tools

Organic synthesis
Catalysis
High-throughput chemistry
Parallel synthesis
Laboratory automation
Liquid handling robotics
Automated analytical and purification systems
Electronic Laboratory Notebook (ELN)

Salary and Benefits

The position provides a salary range of $113K to $156K with multiple ranges. Benefits include company-paid healthcare, flexible spending accounts, voluntary life insurance, 401(k) matching, and uncapped vacation. The workplace is located in a facility in San Diego featuring an onsite gym and dining.

About the Company

Found in 2020 and headquartered in San Diego, Iambic Therapeutics is a clinical-stage life-science and technology company that builds novel medicines through an AI-driven discovery platform. The organization brings together artificial intelligence experts and drug hunters to advance clinical assets internally and through partnerships.

How to Apply

Interested candidates should apply on the official company careers page.

Skills and tech stack

Questions candidates ask

Where is the Research Scientist position located?

The job is based at the company headquarters in San Diego, California.

What qualifications are needed for this role?

Candidates must have either a Ph.D. in Organic Chemistry with 0 to 5 years of industry experience or an MS in Organic Chemistry with a minimum of 8 years of industry experience, along with hands-on experience in high-throughput chemistry and laboratory automation.

What is the salary range for this position?

The salary ranges from $113K to $156K.

What benefits are included with the job?

Benefits include company-paid healthcare, flexible spending accounts, voluntary life insurance, 401(k) matching, uncapped vacation, and access to an onsite gym and dining facility.

What teams will the Research Scientist collaborate with?

The scientist works cross-functionally with chemistry, biology, compound management, AI/ML, software, and automation teams.

Ready to apply?

The application is on the official iambic-therapeutics careers page.

Apply on company site