Associate Director, Clinical Supply Chain, Cambridge, MA
About this role
Proactive, self-driven, highly organized, and entrepreneurial professionals who thrive in agile settings will excel in this position at Isomorphic Labs in Cambridge, MA. The lean Pharmaceutical Sciences and CMC Manufacturing team operates at the intersection of frontier machine learning and drug discovery, building on the Nobel-winning AlphaFold system to design novel molecules and develop life-changing medicines.
As the foundational architect of clinical supply operations, the incoming Associate Director will lead end-to-end clinical trial material planning, vendor management, packaging, labeling, inventory management, and global distribution operations. This role exists to bridge drug manufacturing with clinical operations, scaling systems and processes as the pipeline advances into larger, multi-center trials. The person stepping into this position will act as the primary clinical supply authority, partnering directly with Clinical CROs, IRT providers, and external packaging vendors to ensure uninterrupted patient dosing.
What you will do
- Build and maintain flexible clinical supply models to ensure uninterrupted patient dosing and minimal drug waste.
- Direct secondary packaging, blinding strategies, and label generation for clinical trial supplies in compliance with regional and global standards.
- Manage central and regional clinical depots alongside qualified shipping lines, secure chain-of-custody protocols, and specialty courier operations.
- Implement continuous temperature monitoring solutions across shipments and depot storage while triaging excursions in real time.
- Serve as the primary clinical supply chain liaison to Clinical CROs to synchronize supply readiness with clinical timelines.
- Design system functional specifications, supply buffer strategies, and reorder triggers in partnership with IRT providers.
- Direct technical RFPs, contract negotiations, Statements of Work, and performance metrics for clinical packaging and logistics vendors.
What you need
- Hold a Bachelor’s or Master’s degree in Supply Chain Management, Logistics, Life Sciences, Chemical or Industrial Engineering, Pharmacy, or a related discipline.
- Bring 7 or more years of direct experience in clinical supply chain management, clinical logistics, or investigational material management within a pharmaceutical or biotechnology company.
- Demonstrate proven experience supporting clinical trials with a firm grasp of logistics, rapid-response replenishment, and flexible kit demand.
- Possess practical experience managing secondary packaging, clinical labeling, and depot operations.
- Ensure all clinical supply activities comply strictly with cGMPs, ICH, GDPs, GCPs, and internal quality management systems.
Skills and tech stack
Questions candidates ask
What team will I be working with?
You will serve as the clinical supply authority within a lean Pharmaceutical Sciences & CMC Manufacturing team, acting as a direct partner to Clinical Operations and the larger Clinical Development organization.
What are the core responsibilities regarding vendors?
You will execute operations through external clinical packaging and labeling vendors, central and regional depots, specialized temperature-controlled chain couriers, and Interactive Response Technology providers. Additionally, you will direct technical RFPs, contract negotiations, Statements of Work, and performance metrics for these partners.
How does this role contribute to the company's mission?
As part of an AI-first company that applies frontier machine learning to drug discovery, you will help us reimagine how we bring new medicines to patients. You will act as the foundational architect of our clinical supply operations by scaling systems, processes, and vendor networks as our pipeline advances.
The application is on the official Isomorphic Labs careers page.
Apply on company site