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Staff Machine Learning and Bioinformatics Scientist (Multi-Cancer Early Detection)

NateraUS RemoteMolecular Biology Informatics & Statistics
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Salary
$163,200 — $204K USD
Job type
Full-time
Work mode
Remote
Experience
Senior · 6+ yrs
Posted
9 Oct 2026
Status
Open · checked 7d ago

About this role

The Staff Machine Learning and Bioinformatics Scientist (Multi-Cancer Early Detection) position at Natera is a full-time remote role based in the US that suits experienced quantitative scientists specializing in multi-modal genomic data and cancer signal detection. This professional will design predictive models to identify various cancers from a single blood draw and guide technical projects from initial prototype to clinical validation.

Role Overview

The research team at Natera builds advanced tests to detect multiple cancers through blood samples. This position focuses on creating the statistical and machine learning models that form the core of that diagnostic effort. The selected candidate collaborates directly with clinical experts and molecular biologists to advance methodologies for patient care.

Key Responsibilities

Spearhead the creation of new statistical and machine learning techniques for detecting cancer signals using multi-modal genomic datasets.
Construct interpretable, calibrated models while establishing benchmarks for reproducibility and uncertainty estimation.
Prototype, test, and deploy machine learning models utilizing scalable infrastructure.
Take ownership of vital technical milestones within larger projects and help direct the research strategy of the team.
Partner alongside molecular biologists and clinical specialists to plan and analyze experiments and validation studies.
Conduct code and design reviews to maintain high technical standards across various projects.
Communicate intricate results clearly to both technical and non-technical stakeholders.
Mentor less experienced scientists and foster a collaborative scientific environment.

Requirements

PhD degree in Bioinformatics, Computer Science, Mathematics, or a closely related quantitative discipline.
Six to twelve years of professional experience following the completion of a PhD.
Practical background in designing novel statistical or machine learning analysis methods for complex biological data.
Demonstrated history of technical innovation and leadership in complex methodological projects.
Specialized knowledge in deep learning and multimodal foundation models.
Strong proficiency in Python and related scientific computing tools.
Rigorous scientific approach throughout the research and development lifecycle.
Strong interpersonal and communication abilities for cross-functional teamwork.

Nice to Have

Prior familiarity with epigenomic data and DNA methylation.
Direct experience working with liquid biopsy samples and cell-free DNA.
Background knowledge in cancer diagnostics and genomics.
Previous hands-on application of multimodal foundation models to biological information.

Skills and Tools

Python
Scientific computing ecosystem
Deep learning
Multimodal foundation models
Statistical and machine learning analysis methods

Salary and Benefits

Compensation range of $163,200 to $204,000 USD per year, determined by factors such as skill set, experience depth, certifications, and location.
Comprehensive medical, dental, vision, life, and disability insurance plans for employees and dependents.
Free testing for employees and immediate family members, alongside fertility care services.
Pregnancy and baby bonding leave.
401(k) retirement benefits and commuter benefits.
Employee referral program.

About the Company

Natera functions as a global provider of cell-free DNA testing, focusing on organ health, oncology, and women's health. The organization aims to integrate personalized genetic testing into standard medical care to facilitate earlier and more targeted health interventions.

How to Apply

Interested candidates should apply directly on the official Natera careers page.

Skills and tech stack

Questions candidates ask

What is the salary range for this position?

The salary ranges from $163,200 to $204,000 USD, depending on factors such as candidate experience, skill set, certifications, and location.

Where is this job located?

This is a US Remote position.

What are the educational requirements for applicants?

Applicants must hold a PhD in Bioinformatics, Computer Science, Mathematics, or a related quantitative field.

How many years of experience are required post-PhD?

Candidates need 6 to 12 years of experience post-PhD.

What programming language is required?

Proficiency in Python and its scientific computing ecosystem is required.

Ready to apply?

The application is on the official Natera careers page.

Apply on company site