Staff Software Engineer (AI)

onoshealthSan FranciscoEngineering

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Opens the official onoshealth careers page

Salary

$200K – $275K

Job type

Full-time

Work mode

Remote

Experience

Senior · 5+ yrs

Posted

1 Oct 2026

Status

Open · checked 7d ago

About this role

Onos Health is hiring a hybrid Staff Software Engineer for their artificial intelligence platform in San Francisco to build systems that streamline healthcare administration and reduce waste. This position suits an experienced backend and data professional who wants to shape early-stage artificial intelligence products in the healthcare sector.

Role Overview

The Staff Software Engineer (AI) position at Onos Health focuses on creating and scaling the data platform that helps payers make accurate patient care decisions. The job is based in San Francisco with a hybrid requirement of working from the local office two to three days per week. As an early team member, the professional in this role will handle diverse responsibilities spanning backend development, data engineering, and artificial intelligence integration.

Key Responsibilities

Design and implement large language model and natural language understanding systems to parse clinical notes, categorize patients by care levels, and generate recommendations

Define protocols for artificial intelligence governance, evaluation frameworks, and system benchmarks to guarantee reliability and scalability

Construct scalable data pipelines that adhere strictly to security and privacy protocols

Partner with backend engineers to embed artificial intelligence functions directly into the platform

Operationalize data architectures that review medical records and assess provider adherence to clinical guidelines

Create explainable artificial intelligence models to ensure transparency for medical professionals

Requirements

Minimum of five years of professional background creating and launching production applications in data or backend engineering roles

Practical background building language model applications for unstructured industry documents and connecting them to user interfaces

Familiarity with the operational boundaries of large language models and methods for achieving consistent results

Customer-focused mindset with dedication to constructing behavioral health assessment models

Cooperative attitude geared toward achieving concrete outcomes

Nice to Have

Direct handling of medical records for claims authorization, evaluations, or determining assessment criteria

Background operating as a generalist backend developer

Experience building data pipelines utilizing Python alongside data science and machine learning libraries

Familiarity with healthcare data standards and regulatory practices like HIPAA

Knowledge of modern machine learning operations and infrastructure best practices

Skills and Tools

AWS including ECS, Bedrock, and Cognito

Docker and GitHub Actions

Python, Django, Celery, django-ninja, and django-tenants

PostgreSQL on AWS RDS and S3

GitHub, Jira, CoderabbitAI, Tusk, and Claude

Salary and Benefits

Annual compensation ranging from $200,000 to $275,000 alongside equity offerings

Flexible hybrid schedule with two to three days per week in the San Francisco Financial District office

Unlimited vacation guidelines and paid parental leave

Medical, dental, and vision health coverage

Pre-tax commuter programs and a 401(k) plan

Mentorship from founders and regular team offsites

Equipment provided for the office and home setup

About the Company

Onos Health addresses administrative burdens and ineffective care that cause waste in the American healthcare system. The enterprise builds an artificial intelligence data platform enabling payers to direct patients toward appropriate care and improve affordability. Backed by healthcare investors, the organization collaborates with major health plans.

How to Apply

Candidates should apply on the official company careers page.

Skills and tech stack

AWS ECS Bedrock Cognito Docker Github Actions Python Django Celery django-ninja django-tenants PostgreSQL AWS RDS S3 Github Jira CoderabbitAI Tusk Claude LLM LLMs MLOps

Questions candidates ask

Where is the Staff Software Engineer position located?

The job is a hybrid role based in San Francisco, requiring employees to work from the office 2 to 3 days per week.

What is the salary and equity package for this role?

The compensation ranges from $200K to $275K per year, accompanied by equity offerings.

How many years of experience are required?

Applicants must have 5+ years of experience building and deploying applications in production within a backend or data engineering capacity.

What technologies are used in the tech stack?

The tech stack includes AWS, Docker, Python, Django, Celery, PostgreSQL, S3, GitHub, and various AI tools like Claude.

What benefits are provided besides salary?

Benefits include medical, dental, and vision insurance, 401(k), unlimited vacation, paid parental leave, commuter benefits, and home office setup equipment.

Ready to apply?

The application is on the official onoshealth careers page.

Apply on company site