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Research Engineer - ML Infrastructure

chaidiscoverySan Francisco officeResearch
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Salary
Not listed
Job type
Full-time
Experience
Senior
Posted
24 Sept 2026
Status
Open · checked 7d ago

About this role

This Research Engineer role suits professionals with deep industry experience working with top artificial intelligence and machine learning teams on complex systems and problems. Based at the company office in San Francisco, the position involves developing core frameworks to make machine learning models performant, resource-efficient, and reliable at scale.

Role Overview

Chai Discovery seeks a Research Engineer specializing in machine learning infrastructure for its San Francisco office location. The successful candidate will collaborate closely with fellow engineers and researchers to build core frameworks for model training and evaluation.

Key Responsibilities

Build the training stack across model, layer, and kernel levels while optimizing workloads using parallelism, quantization, and custom kernels.
Profile end-to-end training runs on large GPU clusters to eliminate bottlenecks and failures while monitoring uptime, utilization, and throughput.
Scale new model architectures and training recipes efficiently, transitioning them from early experiments to frontier-scale runs.
Ensure maximum reliability of the machine learning training stack through fault tolerance, checkpointing, and deterministic orchestration for long-running, large-scale jobs.

Requirements

Bring deep industry experience working with top artificial intelligence and machine learning teams on large-scale systems and problems.
Demonstrate strong software system design skills.
Show proficiency in Python along with fluency in PyTorch or JAX.
Possess a technical spike demonstrating deep engagement and exceptional impact on real-world problems and systems.

Skills and Tools

Python
PyTorch
JAX
Custom kernels
Parallelism
Quantization

About the Company

Chai Discovery builds a design suite for molecules by training frontier models that learn foundational biochemical structures and interactions. Pharmaceutical companies such as Eli Lilly, Pfizer, and Novartis utilize the platform for drug discovery programs. The organization values diverse perspectives and maintains a culture centered on high velocity and ownership.

How to Apply

Interested candidates should submit their application directly on the official company careers page.

Skills and tech stack

Questions candidates ask

Where is the Research Engineer position located?

The role is located at the company office in San Francisco.

What programming languages and frameworks are required?

The position requires proficiency in Python along with fluency in either PyTorch or JAX.

What are the primary responsibilities for this role?

Responsibilities include building training stacks across model, layer, and kernel levels, optimizing workloads, profiling training runs on large GPU clusters, scaling model architectures, and ensuring reliability through fault tolerance and checkpointing.

What kind of background is ideal for applicants?

Ideal candidates have deep industry experience working with top artificial intelligence and machine learning teams on complex systems, supported by strong software system design skills and a technical spike showing exceptional impact.

Ready to apply?

The application is on the official chaidiscovery careers page.

Apply on company site